Do not use Advantan: If you are allergic (hypersensitive) to the active substance methylprednisolone aceponate (mpa) or to any of the other ingredients of advantan (see also section 6. Contents of the Pack and other information) if pre-existing eczema or rash has become infected on skin areas affected by a skin inflammation that is red/rosy in colour (rosacea), ulcers, Inflamed diseases of the sebaceous glands (acne vulgaris) or skin folds, groin or under the arm pits (intertrigo acne), or skin diseases accompanied by a thinning of the skin (atrophic skin diseases) on skin that is weeping on skin areas that show a vaccination reaction i.e. That are red or inflamed after being given a vaccine on specific skin inflammation in the area of the upper lip and chin (perioral dermatitis) on bacterial, viral or fungal skin infections (unless treated accordingly with a special Medicine).